Aim and Objective: The purpose of this study was to determine the frequency and morphological patterns of non-melanoma skin cancers (NMSCs) in University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. Materials and Methods: Data of surgical biopsies from the skin received at the Department of Histopathology over a 26-year period (from January 1982 to December 2007) were reviewed. The sources of information were surgical pathology day books, duplicates of histology request form and reports. Corresponding slides were retrieved for histopathology examination. Data were analyzed with SPSS version 17. Results: A total of 187 skin malignancies were encountered. Of these, 63 accounting for 33.7% were NMSCs. Squamous cell carcinoma (SCC) accounted for 45 cases, constituting 24.1% of all malignant skin tumors and 71.4% of NMSCs. Basal cell carcinoma (BCC) accounted for 18 cases (9.6%) of all malignant skin tumors and 28.6% of NMSCs. The peak incidence of SCC and BCC was in the 5 ^th decade of life. The mean age for SCC and BCC was 51.4 ± 1.3 and 46.3 ± 5.2 years, respectively. The male to female ratios for SCC and BCC were 2.4:1 and 1.6:1, respectively. Conclusion: In conclusion, SCC was the most common NMSC. This is similar to reports of other studies in Africans and Black Americans. In contrast, in Caucasian series, BCC was the most common NMSC. The head and neck region was the most common site of these skin cancers.

Epstein-Barr virus (EBV) is said to infect more than 90% of humans worldwide with latent infection for life. A recognized carcinogen, EBV is linked to malignant lymphoma (ML) subtypes of Burkitt's lymphoma, plasmablastic lymphoma, diffuse large cell lymphoma and Hodgkin's lymphoma. We report the association of EBV with ML in a segment of our patient population. Paraffin blocks from the archives of Ahmadu Bello University Teaching Hospital Zaria were used to construct tissue microarray. Sections were stained using 30 monoclonal antibodies for common non-Hodgkin's lymphoma/Hodgkin's lymphoma antigen. Chromogenic in situ hybridization for EBV-encoded RNA was done. Fewer associations of ML with EBV (54-5%) were found than reported elsewhere in Africa.

Objective: The objective of this study was to determine the frequency, morphological patterns, age and sex and site distribution of vascular tumor in Benin-City, Nigeria. Materials and Methods: The study was a 12 year retrospective analysis of all histologically confirmed vascular tumors seen over a 12 year period at the Pathology Department, University of Benin Teaching Hospital, Benin-City, Nigeria. Results: A total of 162 vascular tumors representing 18.6% of all soft-tissue tumors were analyzed. 136 (83.9%) were benign, 24 (14.7%) were malignant while 2 (1.3%) cases were of borderline malignancy. Hemangioma was the most frequently encountered tumor in this series constituting 71% of all vascular tumors and 84.6% of the benign tumors. Kaposi's sarcoma (KS) was the most common malignant vascular tumor comprising 14.8% of these lesions. The majority of these tumors were located in the head and neck region (39.5%) followed by the upper and lower extremities accounting for 16.7% and 14.2% respectively. Conclusion: This study has shown that hemangioma is the most predominant vascular tumor and that KS is the most common malignant vascular tumor in this setting. This is similar to previous reports from other researchers locally and internationally.

Background: Cervical cancer is the leading cause of cancer deaths in women in the developing countries. Human papilloma virus (HPV) has been implicated as the causative agent. Cervical cancer can primarily be prevented by vaccinating girls and women against HPV infection. Acceptability is demonstrated by the willingness of health workers to use these strategies themselves and to recommend them to their daughters and others. Aim: The aim of this study is to determine the awareness and acceptability of HPV vaccine among female health workers and female medical students in Orlu, Imo State, South-eastern Nigeria. Materials and Methods: A questionnaire based cross-sectional survey using 150 female health workers including female clinical medical students selected randomly from the Imo State University Teaching Hospital, Orlu. Results: The awareness of HPV vaccine was high (74.0%). The majority (57.3%) got the information either from conferences or class lectures. Other sources of information were radio, television and journals 5 (28.0%), while 14.6% got the information from their colleagues. Most of the health workers (67.3%) would recommend the vaccine to their adolescent daughters and clients. Most (64.6%) of the respondents did not think that the vaccine would lead to promiscuity. A good number of the respondents think that the vaccine would reduce the incidence of cervical cancer. Conclusion: The awareness of HPV vaccine and among female health workers in Orlu is high. This is very encouraging these female health workers will help in the dissemination of information regarding the use of this vaccine in the primary prevention of cervical cancer.

Hepatoid adenocarcinoma is one of the rarest tumors of the stomach. These tumors produce alpha-fetoprotein (AFP), which can be used as a diagnostic marker. The prognosis is poor compared to conventional adenocarcinoma of the stomach. A case of AFP-producing hepatoid adenocarcinoma stomach in a 55-year-old woman is presented. The patient underwent partial gastrectomy. We focus on the clinical features, imaging, histopathological and biochemical characteristics of the hepatoid variety of adenocarcinoma stomach.

A 36-year-old primiparous woman with one living child presented to our facility with 4 years history of secondary infertility and 20 weeks gestational age sized painful solid pelvic mass. Ultrasound scan, hysterosalpingography and intravenous urography revealed degenerated fibroids, bilateral tubal occlusion and single ectopic right pelvic kidney. Laparotomy revealed the absence of the left ovary and fallopian tube. This is a very rare finding. Whenever unilateral renal agenesis is found, the patient should be investigated for possible genital anomaly.

This is a case report of a day-old 5.6 kg female baby delivered by cesarean section of a known diabetic and hypertensive mother who presented with gangrene of the right forearm and hand. The diagnosis of congenital gangrene in this neonate was purely clinical and maternal diabetes associated with hypertension an etiological possibility.

Inflammatory fibroid polyp (IFP) is a rare non-neoplastic condition, which has been reported to cause gastrointestinal (GI) bleeding and simple mechanical obstruction of the pylorus or small intestine, but rarely intussusception. Only 1-5% of all bowel obstructions in adults are due to intussusception; >90% of cases are associated with lead point lesions. We are presenting a rare case of adult intussuception caused by an IFP as a lead point lesion. Computed tomography (CT) scan is the investigation of choice for diagnosis of intussusception as well as to identify benign or malignant nature of lead point lesions. En bloc resection of the involved bowel, without attempt at reduction, is the recommended surgical procedure for adult intussusception.